| 9/17/2005 | Mississippi St | 21 | @ | Tulane | 14 | ||||
| 9/24/2005 | Tulane | 31 | @ | SMU | 10 | CUSA | |||
| 10/1/2005 | SE Louisiana | 21 | @ | Tulane | 28 | Baton Rouge | |||
| 10/8/2005 | Houston | 35 | @ | Tulane | 14 | CUSA | |||
| 10/14/2005 | UTEP | 45 | @ | Tulane | 21 | CUSA | Ruston LA | ||
| 10/21/2005 | Tulane | 24 | @ | UCF | 34 | CUSA | |||
| 10/29/2005 | Marshall | 27 | @ | Tulane | 26 | CUSA | |||
| 11/5/2005 | Tulane | 21 | @ | Navy | 49 | ||||
| 11/12/2005 | Tulane | 34 | @ | Rice | 42 | CUSA | |||
| 11/19/2005 | Tulsa | 38 | @ | Tulane | 14 | CUSA | |||
| 11/26/2005 | Tulane | 7 | @ | Southern Miss | 26 | CUSA |