| 8/30/2025 | Central Methodist | at | Missouri S&T | at GLV | ||||
| 9/6/2025 | William Penn | at | Central Methodist | |||||
| 9/13/2025 | Central Methodist | at | Saint Ambrose | |||||
| 9/20/2025 | Peru State | at | Central Methodist | |||||
| 9/27/2025 | Central Methodist | at | William Woods | |||||
| 10/4/2025 | Central Methodist | at | MidAmerica Nazarene | |||||
| 10/18/2025 | Benedictine KS | at | Central Methodist | |||||
| 10/25/2025 | Baker | at | Central Methodist | |||||
| 11/1/2025 | Central Methodist | at | Culver-Stockton | |||||
| 11/8/2025 | Central Methodist | at | Missouri Baptist | |||||
| 11/15/2025 | Missouri Valley | at | Central Methodist |