| 9/6/2025 | Virginia U-Lynchburg | at | Roanoke | None (Unk?) | ||||
| 9/13/2025 | Roanoke | at | Greensboro | at USASC | ||||
| 9/27/2025 | Gallaudet | at | Roanoke | |||||
| 10/4/2025 | Randolph-Macon | at | Roanoke | |||||
| 10/11/2025 | Roanoke | at | Bridgewater VA | |||||
| 10/18/2025 | Shenandoah | at | Roanoke | |||||
| 10/25/2025 | Roanoke | at | Hampden-Sydney | |||||
| 11/1/2025 | Guilford | at | Roanoke | |||||
| 11/8/2025 | Roanoke | at | Washington and Lee | |||||
| 11/15/2025 | Roanoke | at | Averett |