| 9/4/2025 | King's | at | Wilkes | MidAC | ||||
| 9/13/2025 | Wilkes | at | New Jersey | at NJAC | ||||
| 9/20/2025 | Muhlenberg | at | Wilkes | Cen | ||||
| 9/27/2025 | Wilkes | at | Montclair State | at NJAC | ||||
| 10/4/2025 | Catholic | at | Wilkes | |||||
| 10/11/2025 | Wilkes | at | Moravian | |||||
| 10/25/2025 | Wilkes | at | Lycoming | |||||
| 11/1/2025 | Juniata | at | Wilkes | |||||
| 11/8/2025 | Wilkes | at | Susquehanna | |||||
| 11/15/2025 | Western Connecticut | at | Wilkes |