| 8/30/2025 | Central Methodist | at | Missouri S&T | HAAC (NAIA) | ||||
| 9/6/2025 | Missouri S&T | at | Northeastern State | at D2Ind | ||||
| 9/13/2025 | Missouri S&T | at | Missouri Western | at MAIAA | ||||
| 9/20/2025 | Truman State | at | Missouri S&T | |||||
| 9/27/2025 | Missouri S&T | at | Southwest Baptist | |||||
| 10/4/2025 | Upper Iowa | at | Missouri S&T | |||||
| 10/11/2025 | Indianapolis | at | Missouri S&T | |||||
| 10/18/2025 | Missouri S&T | at | McKendree | |||||
| 10/25/2025 | Missouri S&T | at | Quincy | |||||
| 11/1/2025 | William Jewell | at | Missouri S&T | |||||
| 11/8/2025 | Missouri S&T | at | Lincoln MO |