| 9/6/2025 | Winston-Salem State | at | Mars Hill | CIAA | ||||
| 9/13/2025 | Carson-Newman | at | Mars Hill | |||||
| 9/20/2025 | Anderson SC | at | Mars Hill | |||||
| 9/27/2025 | Mary Hardin-Baylor | at | Mars Hill | ASWC (D3) | ||||
| 10/4/2025 | Mars Hill | at | Catawba | |||||
| 10/11/2025 | Emory & Henry | at | Mars Hill | |||||
| 10/18/2025 | Mars Hill | at | Newberry | |||||
| 10/25/2025 | Lenoir-Rhyne | at | Mars Hill | |||||
| 11/1/2025 | Mars Hill | at | Tusculum | |||||
| 11/8/2025 | Virginia-Wise | at | Mars Hill | |||||
| 11/15/2025 | Mars Hill | at | Wingate |