| 8/30/2025 | Elizabeth City State | at | Chowan | CIAA | ||||
| 9/6/2025 | West Alabama | at | Chowan | GSC | ||||
| 9/20/2025 | Valdosta State | at | Chowan | GSC | ||||
| 9/27/2025 | Chowan | at | Shorter | |||||
| 10/4/2025 | North Greenville | at | Chowan | |||||
| 10/11/2025 | Chowan | at | West Florida | at GSC | ||||
| 10/18/2025 | Chowan | at | Barton | |||||
| 10/25/2025 | UNC Pembroke | at | Chowan | |||||
| 11/1/2025 | Chowan | at | Erskine | |||||
| 11/8/2025 | Ferrum | at | Chowan |