| 8/30/2025 | Central Oklahoma | at | Texas-Permian Basin | at LSC | ||||
| 9/6/2025 | Pittsburg State | at | Central Oklahoma | |||||
| 9/20/2025 | Washburn | at | Central Oklahoma | |||||
| 9/27/2025 | Central Oklahoma | at | Northwest Missouri State | |||||
| 10/4/2025 | Central Missouri | at | Central Oklahoma | |||||
| 10/11/2025 | Central Oklahoma | at | Fort Hays State | |||||
| 10/18/2025 | Emporia State | at | Central Oklahoma | |||||
| 10/25/2025 | Northeastern State | at | Central Oklahoma | D2Ind | ||||
| 11/1/2025 | Central Oklahoma | at | Nebraska-Kearney | |||||
| 11/8/2025 | Missouri Southern | at | Central Oklahoma | |||||
| 11/15/2025 | Central Oklahoma | at | Missouri Western |