| 8/29/2025 | Western Illinois | at | Illinois | at B10 | ||||
| 9/5/2025 | Western Illinois | at | Northwestern | at B10 | ||||
| 9/13/2025 | Valparaiso | at | Western Illinois | Pio | ||||
| 9/20/2025 | Western Illinois | at | Eastern Washington | at BSky | ||||
| 9/27/2025 | Eastern Illinois | at | Western Illinois | |||||
| 10/4/2025 | Western Illinois | at | Tennessee Tech | |||||
| 10/11/2025 | Western Illinois | at | Tennessee-Martin | |||||
| 10/18/2025 | Charleston Southern | at | Western Illinois | |||||
| 10/25/2025 | Western Illinois | at | Tennessee State | |||||
| 11/8/2025 | Lindenwood | at | Western Illinois | |||||
| 11/15/2025 | SE Missouri State | at | Western Illinois | |||||
| 11/22/2025 | Western Illinois | at | Gardner-Webb |