| 8/30/2025 | Prairie View | at | Texas Southern | |||||
| 9/6/2025 | Texas Southern | at | California | at ACC | ||||
| 9/13/2025 | Lamar | at | Texas Southern | SLC | ||||
| 9/27/2025 | Texas Southern | at | Mississippi Valley State | |||||
| 10/4/2025 | Ark Pine Bluff | at | Texas Southern | |||||
| 10/11/2025 | Texas Southern | at | Grambling | |||||
| 10/18/2025 | Virginia U-Lynchburg | at | Texas Southern | None (Unk?) | ||||
| 11/1/2025 | Alcorn State | at | Texas Southern | |||||
| 11/8/2025 | Texas Southern | at | Alabama State | |||||
| 11/15/2025 | Texas Southern | at | Southern | |||||
| 11/22/2025 | Alabama A&M | at | Texas Southern |