| 8/30/2025 | Cal Poly | at | San Diego | at Pio | ||||
| 9/6/2025 | Cal Poly | at | Utah | at B12 | ||||
| 9/13/2025 | Western Oregon | at | Cal Poly | LSC (D2) | ||||
| 9/20/2025 | Cal Poly | at | Stephen F. Austin | at SLC | ||||
| 9/27/2025 | Cal Poly | at | Sacramento State | |||||
| 10/4/2025 | UC Davis | at | Cal Poly | |||||
| 10/11/2025 | Cal Poly | at | Montana | |||||
| 10/25/2025 | Montana State | at | Cal Poly | |||||
| 11/1/2025 | Portland State | at | Cal Poly | |||||
| 11/8/2025 | Cal Poly | at | Idaho State | |||||
| 11/15/2025 | Cal Poly | at | Northern Arizona | |||||
| 11/22/2025 | Eastern Washington | at | Cal Poly |