| 8/23/2025 | Sam Houston | at | Western Kentucky | |||||
| 8/30/2025 | North Alabama | at | Western Kentucky | UAC (1AA) | ||||
| 9/6/2025 | Western Kentucky | at | Toledo | at MAC | ||||
| 9/20/2025 | Nevada | at | Western Kentucky | MW | ||||
| 9/27/2025 | Western Kentucky | at | Missouri State | |||||
| 10/3/2025 | Western Kentucky | at | Delaware | |||||
| 10/14/2025 | Florida Intl | at | Western Kentucky | |||||
| 10/21/2025 | Western Kentucky | at | Louisiana Tech | |||||
| 11/1/2025 | New Mexico State | at | Western Kentucky | |||||
| 11/15/2025 | Middle Tenn State | at | Western Kentucky | |||||
| 11/22/2025 | Western Kentucky | at | LSU | at SEC | ||||
| 11/29/2025 | Western Kentucky | at | Jacksonville State |