| 8/30/2025 | Rice | at | UL Lafayette | AAC | ||||
| 9/6/2025 | McNeese State | at | UL Lafayette | SLC (1AA) | ||||
| 9/13/2025 | UL Lafayette | at | Missouri | at SEC | ||||
| 9/20/2025 | UL Lafayette | at | Eastern Michigan | at MAC | ||||
| 9/27/2025 | Marshall | at | UL Lafayette | |||||
| 10/11/2025 | UL Lafayette | at | James Madison | |||||
| 10/18/2025 | Southern Miss | at | UL Lafayette | |||||
| 10/25/2025 | UL Lafayette | at | Troy | |||||
| 11/1/2025 | UL Lafayette | at | South Alabama | |||||
| 11/8/2025 | Texas State | at | UL Lafayette | |||||
| 11/20/2025 | UL Lafayette | at | Arkansas State | |||||
| 11/29/2025 | UL Monroe | at | UL Lafayette |