| 8/30/2025 | Toledo | at | Kentucky | at SEC | ||||
| 9/6/2025 | Western Kentucky | at | Toledo | CUSA | ||||
| 9/13/2025 | Morgan State | at | Toledo | MEAC (1AA) | ||||
| 9/20/2025 | Toledo | at | Western Michigan | |||||
| 9/27/2025 | Akron | at | Toledo | |||||
| 10/11/2025 | Toledo | at | Bowling Green | |||||
| 10/18/2025 | Kent State | at | Toledo | |||||
| 10/25/2025 | Toledo | at | Washington State | at Ind | ||||
| 11/5/2025 | Northern Illinois | at | Toledo | |||||
| 11/12/2025 | Toledo | at | Miami-Ohio | |||||
| 11/22/2025 | Ball State | at | Toledo | |||||
| 11/29/2025 | Toledo | at | Central Michigan |