| 8/30/2025 | Syracuse | vs | Tennessee | Atlanta GA | ACC | |||
| 9/6/2025 | East Tennessee St | at | Tennessee | SoCon (1AA) | ||||
| 9/13/2025 | Georgia | at | Tennessee | |||||
| 9/20/2025 | UAB | at | Tennessee | AAC | ||||
| 9/27/2025 | Tennessee | at | Mississippi State | |||||
| 10/11/2025 | Arkansas | at | Tennessee | |||||
| 10/18/2025 | Tennessee | at | Alabama | |||||
| 10/25/2025 | Tennessee | at | Kentucky | |||||
| 11/1/2025 | Oklahoma | at | Tennessee | |||||
| 11/15/2025 | New Mexico State | at | Tennessee | CUSA | ||||
| 11/22/2025 | Tennessee | at | Florida | |||||
| 11/29/2025 | Vanderbilt | at | Tennessee |