| 8/28/2025 | Tennessee-Martin | at | Oklahoma State | BigS (1AA) | ||||
| 9/6/2025 | Oklahoma State | at | Oregon | at B10 | ||||
| 9/19/2025 | Tulsa | at | Oklahoma State | AAC | ||||
| 9/27/2025 | Baylor | at | Oklahoma State | |||||
| 10/4/2025 | Oklahoma State | at | Arizona | |||||
| 10/11/2025 | Houston | at | Oklahoma State | |||||
| 10/18/2025 | Cincinnati | at | Oklahoma State | |||||
| 10/25/2025 | Oklahoma State | at | Texas Tech | |||||
| 11/1/2025 | Oklahoma State | at | Kansas | |||||
| 11/15/2025 | Kansas State | at | Oklahoma State | |||||
| 11/22/2025 | Oklahoma State | at | UCF | |||||
| 11/29/2025 | Iowa State | at | Oklahoma State |