| 8/28/2025 | Ohio | at | Rutgers | at B10 | ||||
| 9/6/2025 | West Virginia | at | Ohio | B12 | ||||
| 9/13/2025 | Ohio | at | Ohio State | at B10 | ||||
| 9/20/2025 | Gardner-Webb | at | Ohio | BigS (1AA) | ||||
| 9/27/2025 | Bowling Green | at | Ohio | |||||
| 10/4/2025 | Ohio | at | Ball State | |||||
| 10/18/2025 | Northern Illinois | at | Ohio | |||||
| 10/25/2025 | Ohio | at | Eastern Michigan | |||||
| 11/4/2025 | Miami-Ohio | at | Ohio | |||||
| 11/11/2025 | Ohio | at | Western Michigan | |||||
| 11/18/2025 | Massachusetts | at | Ohio | |||||
| 11/28/2025 | Ohio | at | Buffalo |