| 8/30/2025 | Northwestern | at | Tulane | at AAC | ||||
| 9/5/2025 | Western Illinois | at | Northwestern | BigS (1AA) | ||||
| 9/13/2025 | Oregon | at | Northwestern | |||||
| 9/27/2025 | UCLA | at | Northwestern | |||||
| 10/4/2025 | UL Monroe | at | Northwestern | SBC | ||||
| 10/11/2025 | Northwestern | at | Penn State | |||||
| 10/18/2025 | Purdue | at | Northwestern | |||||
| 10/25/2025 | Northwestern | at | Nebraska | |||||
| 11/7/2025 | Northwestern | at | Southern California | |||||
| 11/15/2025 | Michigan | vs | Northwestern | Chicago IL | ||||
| 11/22/2025 | Minnesota | vs | Northwestern | Chicago IL | ||||
| 11/29/2025 | Northwestern | at | Illinois |