| 8/30/2025 | Holy Cross | at | Northern Illinois | Pat (1AA) | ||||
| 9/5/2025 | Northern Illinois | at | Maryland | at B10 | ||||
| 9/20/2025 | Northern Illinois | at | Mississippi State | at SEC | ||||
| 9/27/2025 | San Diego State | at | Northern Illinois | MW | ||||
| San Diego State | at | Northern Illinois | MW | |||||
| 10/4/2025 | Miami-Ohio | at | Northern Illinois | |||||
| 10/11/2025 | Northern Illinois | at | Eastern Michigan | |||||
| 10/18/2025 | Northern Illinois | at | Ohio | |||||
| 10/25/2025 | Ball State | at | Northern Illinois | |||||
| 11/5/2025 | Northern Illinois | at | Toledo | |||||
| 11/12/2025 | Northern Illinois | at | Massachusetts | |||||
| 11/18/2025 | Western Michigan | at | Northern Illinois | |||||
| 11/28/2025 | Kent State | at | Northern Illinois |