| 9/1/2025 | TCU | at | North Carolina | B12 | ||||
| 9/6/2025 | North Carolina | at | UNC-Charlotte | at AAC | ||||
| 9/13/2025 | Richmond | at | North Carolina | Pat (1AA) | ||||
| 9/20/2025 | North Carolina | at | UCF | at B12 | ||||
| 10/4/2025 | Clemson | at | North Carolina | |||||
| 10/17/2025 | North Carolina | at | California | |||||
| 10/25/2025 | Virginia | at | North Carolina | |||||
| 10/31/2025 | North Carolina | at | Syracuse | |||||
| 11/8/2025 | Stanford | at | North Carolina | |||||
| 11/15/2025 | North Carolina | at | Wake Forest | |||||
| 11/22/2025 | Duke | at | North Carolina | |||||
| 11/29/2025 | North Carolina | at | North Carolina State |