| 8/28/2025 | Cincinnati | vs | Nebraska | Kansas City MO | B12 | |||
| 9/6/2025 | Akron | at | Nebraska | MAC | ||||
| 9/13/2025 | Houston Christian | at | Nebraska | SLC (1AA) | ||||
| 9/20/2025 | Michigan | at | Nebraska | |||||
| 10/4/2025 | Michigan State | at | Nebraska | |||||
| 10/11/2025 | Nebraska | at | Maryland | |||||
| 10/17/2025 | Nebraska | at | Minnesota | |||||
| 10/25/2025 | Northwestern | at | Nebraska | |||||
| 11/1/2025 | Southern California | at | Nebraska | |||||
| 11/8/2025 | Nebraska | at | UCLA | |||||
| 11/22/2025 | Nebraska | at | Penn State | |||||
| 11/28/2025 | Iowa | at | Nebraska |