| 8/28/2025 | Central Arkansas | at | Missouri | UAC (1AA) | ||||
| 9/6/2025 | Kansas | at | Missouri | B12 | ||||
| 9/13/2025 | UL Lafayette | at | Missouri | SBC | ||||
| 9/20/2025 | South Carolina | at | Missouri | |||||
| 9/27/2025 | Massachusetts | at | Missouri | MAC | ||||
| 10/11/2025 | Alabama | at | Missouri | |||||
| 10/18/2025 | Missouri | at | Auburn | |||||
| 10/25/2025 | Missouri | at | Vanderbilt | |||||
| 11/8/2025 | Texas A&M | at | Missouri | |||||
| 11/15/2025 | Mississippi State | at | Missouri | |||||
| 11/22/2025 | Missouri | at | Oklahoma | |||||
| 11/29/2025 | Missouri | at | Arkansas |