| 8/30/2025 | Georgia State | at | Mississippi | SBC | ||||
| 9/6/2025 | Mississippi | at | Kentucky | |||||
| 9/13/2025 | Arkansas | at | Mississippi | |||||
| 9/20/2025 | Tulane | at | Mississippi | AAC | ||||
| 9/27/2025 | LSU | at | Mississippi | |||||
| 10/11/2025 | Washington State | at | Mississippi | Ind | ||||
| 10/18/2025 | Mississippi | at | Georgia | |||||
| 10/25/2025 | Mississippi | at | Oklahoma | |||||
| 11/1/2025 | South Carolina | at | Mississippi | |||||
| 11/8/2025 | The Citadel | at | Mississippi | SoCon (1AA) | ||||
| 11/15/2025 | Florida | at | Mississippi | |||||
| 11/28/2025 | Mississippi | at | Mississippi State |