| 8/30/2025 | New Mexico | at | Michigan | MW | ||||
| 9/6/2025 | Michigan | at | Oklahoma | at SEC | ||||
| 9/13/2025 | Central Michigan | at | Michigan | MAC | ||||
| 9/20/2025 | Michigan | at | Nebraska | |||||
| 10/4/2025 | Wisconsin | at | Michigan | |||||
| 10/11/2025 | Michigan | at | Southern California | |||||
| 10/18/2025 | Washington | at | Michigan | |||||
| 10/25/2025 | Michigan | at | Michigan State | |||||
| 11/1/2025 | Purdue | at | Michigan | |||||
| 11/15/2025 | Michigan | vs | Northwestern | Chicago IL | ||||
| 11/22/2025 | Michigan | at | Maryland | |||||
| 11/29/2025 | Ohio State | at | Michigan |