| 8/30/2025 | Toledo | at | Kentucky | MAC | ||||
| 9/6/2025 | Mississippi | at | Kentucky | |||||
| 9/13/2025 | Eastern Michigan | at | Kentucky | MAC | ||||
| 9/27/2025 | Kentucky | at | South Carolina | |||||
| 10/4/2025 | Kentucky | at | Georgia | |||||
| 10/18/2025 | Texas | at | Kentucky | |||||
| 10/25/2025 | Tennessee | at | Kentucky | |||||
| 11/1/2025 | Kentucky | at | Auburn | |||||
| 11/8/2025 | Florida | at | Kentucky | |||||
| 11/15/2025 | Tennessee Tech | at | Kentucky | BigS (1AA) | ||||
| 11/22/2025 | Kentucky | at | Vanderbilt | |||||
| 11/29/2025 | Kentucky | at | Louisville | at ACC |