| 8/29/2025 | Western Illinois | at | Illinois | BigS (1AA) | ||||
| 9/6/2025 | Illinois | at | Duke | at ACC | ||||
| 9/13/2025 | Western Michigan | at | Illinois | MAC | ||||
| 9/20/2025 | Illinois | at | Indiana | |||||
| 9/27/2025 | Southern California | at | Illinois | |||||
| 10/4/2025 | Illinois | at | Purdue | |||||
| 10/11/2025 | Ohio State | at | Illinois | |||||
| 10/25/2025 | Illinois | at | Washington | |||||
| 11/1/2025 | Rutgers | at | Illinois | |||||
| 11/15/2025 | Maryland | at | Illinois | |||||
| 11/22/2025 | Illinois | at | Wisconsin | |||||
| 11/29/2025 | Northwestern | at | Illinois |