| 8/30/2025 | Eastern Michigan | at | Texas State | at SBC | ||||
| 9/6/2025 | LIU | at | Eastern Michigan | NE (1AA) | ||||
| 9/13/2025 | Eastern Michigan | at | Kentucky | at SEC | ||||
| 9/20/2025 | UL Lafayette | at | Eastern Michigan | SBC | ||||
| 9/27/2025 | Eastern Michigan | at | Central Michigan | |||||
| 10/4/2025 | Eastern Michigan | at | Buffalo | |||||
| 10/11/2025 | Northern Illinois | at | Eastern Michigan | |||||
| 10/18/2025 | Eastern Michigan | at | Miami-Ohio | |||||
| 10/25/2025 | Ohio | at | Eastern Michigan | |||||
| 11/8/2025 | Bowling Green | at | Eastern Michigan | |||||
| 11/15/2025 | Eastern Michigan | at | Ball State | |||||
| 11/25/2025 | Western Michigan | at | Eastern Michigan |