| 8/29/2025 | Georgia Tech | at | Colorado | ACC | ||||
| 9/6/2025 | Delaware | at | Colorado | CUSA | ||||
| 9/12/2025 | Colorado | at | Houston | |||||
| 9/20/2025 | Wyoming | at | Colorado | MW | ||||
| 9/27/2025 | BYU | at | Colorado | |||||
| 10/4/2025 | Colorado | at | TCU | |||||
| 10/11/2025 | Iowa State | at | Colorado | |||||
| 10/25/2025 | Colorado | at | Utah | |||||
| 11/1/2025 | Arizona | at | Colorado | |||||
| 11/8/2025 | Colorado | at | West Virginia | |||||
| 11/22/2025 | Arizona State | at | Colorado | |||||
| 11/29/2025 | Colorado | at | Kansas State |