| 8/23/2025 | Southern | vs | North Carolina Central | Atlanta GA | vs MEAC | |||
| 8/28/2025 | Alabama State | at | UAB | @ AAC (1A) | ||||
| Alcorn State | at | Northwestern State | @ SLC | |||||
| 8/29/2025 | Bethune-Cookman | at | Florida Intl | @ CUSA (1A) | ||||
| 8/30/2025 | Alabama A&M | at | Arkansas | @ SEC (1A) | ||||
| Howard | vs | Florida A&M | Miami Gardens FL | vs MEAC | ||||
| Langston | vs | Grambling | Shreveport LA | vs Soon (NAIA) | ||||
| Hampton | at | Jackson State | CAAF | |||||
| Southern | at | Mississippi Valley State | ||||||
| Prairie View | at | Texas Southern | ||||||
| Ark Pine Bluff | at | Texas Tech | @ B12 (1A) | |||||
| 9/6/2025 | Alcorn State | at | Alabama A&M | |||||
| Texas Southern | at | California | @ ACC (1A) | |||||
| Ark Pine Bluff | at | Central Arkansas | @ UAC | |||||
| Florida A&M | at | Florida Atlantic | @ AAC (1A) | |||||
| Bethune-Cookman | at | Miami-Florida | @ ACC (1A) | |||||
| Grambling | at | Ohio State | @ B10 (1A) | |||||
| Texas-Rio Grande Valley | at | Prairie View | SLC | |||||
| Jackson State | at | Southern Miss | @ SBC (1A) | |||||
| Alabama State | at | Southern | ||||||
| Mississippi Valley State | at | Tarleton State | @ UAC | |||||
| 9/13/2025 | Miles | at | Alabama State | SIAC (D2) | ||||
| Lincoln CA | at | Ark Pine Bluff | None (Unk?) | |||||
| Albany State GA | at | Florida A&M | SIAC (D2) | |||||
| Southern | at | Fresno State | @ MW (1A) | |||||
| Kentucky State | at | Grambling | SIAC (D2) | |||||
| Tuskegee | at | Jackson State | SIAC (D2) | |||||
| Alcorn State | at | Mississippi State | @ SEC (1A) | |||||
| Prairie View | at | Rice | @ AAC (1A) | |||||
| Mississippi Valley State | at | Southeastern Louisiana | @ SLC | |||||
| Bethune-Cookman | at | South Carolina State | @ MEAC | |||||
| Alabama A&M | at | Tennessee State | @ BigS | |||||
| Lamar | at | Texas Southern | SLC | |||||
| 9/20/2025 | Lane | at | Alabama A&M | SIAC (D2) | ||||
| Edward Waters | at | Bethune-Cookman | SIAC (D2) | |||||
| East Texas A&M | at | Grambling | SLC | |||||
| Northwestern State | at | Prairie View | SLC | |||||
| 9/27/2025 | Alcorn State | vs | Ark Pine Bluff | Memphis TN | ||||
| Alabama A&M | at | Bethune-Cookman | ||||||
| Alabama State | at | Florida A&M | ||||||
| Texas Southern | at | Mississippi Valley State | ||||||
| Grambling | vs | Prairie View | Dallas TX | |||||
| Jackson State | at | Southern | ||||||
| 10/4/2025 | Bethune-Cookman | at | Alabama State | |||||
| Prairie View | at | Alcorn State | ||||||
| Mississippi Valley State | vs | Florida A&M | Atlanta GA | |||||
| Alabama A&M | vs | Jackson State | Mobile AL | |||||
| Ark Pine Bluff | at | Texas Southern | ||||||
| 10/11/2025 | Mississippi Valley State | at | Alabama A&M | |||||
| Lincoln CA | at | Alcorn State | None (Unk?) | |||||
| Southern | at | Bethune-Cookman | ||||||
| North Carolina Central | at | Florida A&M | MEAC | |||||
| Texas Southern | at | Grambling | ||||||
| Alabama State | at | Jackson State | ||||||
| 10/18/2025 | Grambling | at | Ark Pine Bluff | |||||
| Alcorn State | at | Florida A&M | ||||||
| Lincoln CA | at | Mississippi Valley State | None (Unk?) | |||||
| Prairie View | at | Southern | ||||||
| Virginia U-Lynchburg | at | Texas Southern | None (Unk?) | |||||
| 10/25/2025 | Alabama A&M | vs | Alabama State | Birmingham AL | ||||
| Mississippi Valley State | at | Alcorn State | ||||||
| Ark Pine Bluff | at | Bethune-Cookman | ||||||
| Jackson State | vs | Grambling | Las Vegas NV | |||||
| Lincoln CA | at | Prairie View | None (Unk?) | |||||
| Florida A&M | at | Southern | ||||||
| 11/1/2025 | Southern | at | Ark Pine Bluff | |||||
| Mississippi Valley State | at | Bethune-Cookman | ||||||
| Jackson State | at | Florida A&M | ||||||
| Alabama A&M | at | Grambling | ||||||
| Alabama State | at | Prairie View | ||||||
| Alcorn State | at | Texas Southern | ||||||
| 11/8/2025 | Prairie View | at | Alabama A&M | |||||
| Texas Southern | at | Alabama State | ||||||
| Southern | at | Alcorn State | ||||||
| Florida A&M | at | Ark Pine Bluff | ||||||
| Bethune-Cookman | at | Grambling | ||||||
| Jackson State | at | Mississippi Valley State | ||||||
| 11/15/2025 | Florida A&M | at | Alabama A&M | |||||
| Mississippi Valley State | vs | Alabama State | Mobile AL | |||||
| Grambling | at | Alcorn State | ||||||
| Bethune-Cookman | at | Jackson State | ||||||
| Ark Pine Bluff | at | Prairie View | ||||||
| Texas Southern | at | Southern | ||||||
| 11/22/2025 | Ark Pine Bluff | at | Alabama State | |||||
| Florida A&M | vs | Bethune-Cookman | Orlando FL | |||||
| Alcorn State | at | Jackson State | ||||||
| Mississippi Valley State | at | Prairie View | ||||||
| Alabama A&M | at | Texas Southern | ||||||
| 11/27/2025 | Tuskegee | at | Alabama State | SIAC (D2) | ||||
| 11/29/2025 | Grambling | vs | Southern | New Orleans LA |