| 8/28/2025 | Sioux Falls | | at | Black Hills State | | | | @ RMAC |
| Minot State | | at | Emporia State | | | | @ MAIAA |
| Midland U. | | at | Mary | | | | GPAC (NAIA) |
| Bemidji State | | at | Michigan Tech | | | | @ GLIAC |
| Northwest Missouri State | | at | Minnesota State-Mankato | | | | MAIAA |
| Minnesota State-Moorhead | | at | Northern Michigan | | | | @ GLIAC |
| Concordia-St Paul | | at | Quincy | | | | @ GLV |
| Nebraska-Kearney | | at | Wayne State NE | | | | MAIAA |
| Minnesota-Duluth | | vs | Winona State | | | Eagan MN | |
| 8/30/2025 | Missouri Western | | at | Augustana SD | | | | MAIAA |
| 9/6/2025 | Jamestown | | at | Augustana SD | | | | |
| Minnesota-Duluth | | at | Concordia-St Paul | | | | |
| Minot State | | at | Minnesota State-Mankato | | | | |
| Northern State | | at | Sioux Falls | | | | |
| Minnesota State-Moorhead | | at | Southwest Minnesota State | | | | |
| Mary | | at | Wayne State NE | | | | |
| Bemidji State | | at | Winona State | | | | |
| 9/13/2025 | Sioux Falls | | at | Bemidji State | | | | |
| Southwest Minnesota State | | at | Jamestown | | | | |
| Augustana SD | | at | Mary | | | | |
| Winona State | | at | Minnesota State-Moorhead | | | | |
| Minnesota State-Mankato | | at | Minnesota-Duluth | | | | |
| Concordia-St Paul | | at | Minot State | | | | |
| Wayne State NE | | at | Northern State | | | | |
| 9/20/2025 | Augustana SD | | at | Bemidji State | | | | |
| Minnesota State-Mankato | | at | Jamestown | | | | |
| Wayne State NE | | at | Minnesota State-Moorhead | | | | |
| Concordia-St Paul | | at | Northern State | | | | |
| Minnesota-Duluth | | at | Sioux Falls | | | | |
| Mary | | at | Southwest Minnesota State | | | | |
| Minot State | | at | Winona State | | | | |
| 9/27/2025 | Winona State | | at | Augustana SD | | | | |
| Jamestown | | at | Concordia-St Paul | | | | |
| Northern State | | at | Mary | | | | |
| Sioux Falls | | at | Minnesota State-Mankato | | | | |
| Minnesota State-Moorhead | | at | Minnesota-Duluth | | | | |
| Bemidji State | | at | Minot State | | | | |
| Southwest Minnesota State | | at | Wayne State NE | | | | |
| 10/4/2025 | Northern State | | at | Bemidji State | | | | |
| Minnesota State-Mankato | | at | Concordia-St Paul | | | | |
| Mary | | at | Jamestown | | | | |
| Minot State | | at | Minnesota State-Moorhead | | | | |
| Southwest Minnesota State | | at | Minnesota-Duluth | | | | |
| Augustana SD | | at | Sioux Falls | | | | |
| Wayne State NE | | at | Winona State | | | | |
| 10/11/2025 | Concordia-St Paul | | at | Augustana SD | | | | |
| Minnesota State-Moorhead | | at | Mary | | | | |
| Winona State | | at | Minnesota State-Mankato | | | | |
| Jamestown | | at | Minot State | | | | |
| Minnesota-Duluth | | at | Northern State | | | | |
| Sioux Falls | | at | Southwest Minnesota State | | | | |
| Bemidji State | | at | Wayne State NE | | | | |
| 10/18/2025 | Southwest Minnesota State | | at | Northern State | | | | |
| 10/25/2025 | Jamestown | | at | Bemidji State | | | | |
| Mary | | at | Minnesota-Duluth | | | | |
| Sioux Falls | | at | Minot State | | | | |
| Minnesota State-Moorhead | | at | Northern State | | | | |
| Augustana SD | | at | Southwest Minnesota State | | | | |
| Minnesota State-Mankato | | at | Wayne State NE | | | | |
| Concordia-St Paul | | at | Winona State | | | | |
| 11/1/2025 | Northern State | | at | Augustana SD | | | | |
| Wayne State NE | | at | Concordia-St Paul | | | | |
| Minnesota-Duluth | | at | Jamestown | | | | |
| Minot State | | at | Mary | | | | |
| Southwest Minnesota State | | at | Minnesota State-Mankato | | | | |
| Bemidji State | | at | Minnesota State-Moorhead | | | | |
| Winona State | | at | Sioux Falls | | | | |
| 11/8/2025 | Minnesota State-Mankato | | at | Augustana SD | | | | |
| Winona State | | at | Mary | | | | |
| Jamestown | | at | Minnesota State-Moorhead | | | | |
| Bemidji State | | at | Minnesota-Duluth | | | | |
| Minot State | | at | Northern State | | | | |
| Wayne State NE | | at | Sioux Falls | | | | |
| Concordia-St Paul | | at | Southwest Minnesota State | | | | |
| 11/15/2025 | Mary | | at | Bemidji State | | | | |
| Sioux Falls | | at | Concordia-St Paul | | | | |
| Northern State | | at | Jamestown | | | | |
| Minnesota State-Moorhead | | at | Minnesota State-Mankato | | | | |
| Minnesota-Duluth | | at | Minot State | | | | |
| Augustana SD | | at | Wayne State NE | | | | |
| Southwest Minnesota State | | at | Winona State | | | | |