| 8/28/2025 | McKendree | at | Indiana State | GLV (D2) | ||||
| Mercyhurst | at | Youngstown State | NE | |||||
| 8/30/2025 | Murray State | at | East Tennessee St | @ SoCon | ||||
| South Dakota | at | Iowa State | @ B12 (1A) | |||||
| North Dakota | at | Kansas State | @ B12 (1A) | |||||
| Butler | at | Northern Iowa | Pio | |||||
| Illinois State | at | Oklahoma | @ SEC (1A) | |||||
| Sacramento State | at | South Dakota State | BSky | |||||
| Thomas More | at | Southern Illinois | GMAC (D2) | |||||
| North Dakota State | at | The Citadel | @ SoCon | |||||
| 9/6/2025 | Morehead State | at | Illinois State | Pio | ||||
| Eastern Illinois | at | Indiana State | BigS | |||||
| South Dakota | at | Lamar | @ SLC | |||||
| South Dakota State | at | Montana State | @ BSky | |||||
| Southeastern Louisiana | at | Murray State | SLC | |||||
| Portland State | at | North Dakota | BSky | |||||
| Southern Illinois | at | Purdue | @ B10 (1A) | |||||
| North Dakota State | at | Tennessee State | @ BigS | |||||
| Northern Iowa | at | Wyoming | @ MW (1A) | |||||
| Robert Morris | at | Youngstown State | NE | |||||
| 9/12/2025 | Indiana State | at | Indiana | @ B10 (1A) | ||||
| 9/13/2025 | Illinois State | at | Eastern Illinois | @ BigS | ||||
| Murray State | at | Georgia State | @ SBC (1A) | |||||
| Youngstown State | at | Michigan State | @ B10 (1A) | |||||
| North Dakota | at | Montana | @ BSky | |||||
| SE Missouri State | at | North Dakota State | BigS | |||||
| Eastern Washington | at | Northern Iowa | BSky | |||||
| Northern Colorado | at | South Dakota | BSky | |||||
| Drake | at | South Dakota State | Pio | |||||
| Southern Illinois | at | Tennessee-Martin | @ BigS | |||||
| 9/20/2025 | North Alabama | at | Illinois State | UAC | ||||
| Murray State | at | Jacksonville State | @ CUSA (1A) | |||||
| Indiana State | at | Montana | @ BSky | |||||
| Valparaiso | at | North Dakota | Pio | |||||
| Southern Illinois | at | SE Missouri State | @ BigS | |||||
| Drake | at | South Dakota | Pio | |||||
| Youngstown State | at | Towson | @ CAAF | |||||
| Northern Iowa | at | Utah Tech | @ UAC | |||||
| 9/27/2025 | South Dakota | at | North Dakota State | |||||
| Mercyhurst | at | South Dakota State | NE | |||||
| 10/4/2025 | North Dakota State | at | Illinois State | |||||
| North Dakota | at | Northern Iowa | ||||||
| Murray State | at | South Dakota | ||||||
| Indiana State | at | Southern Illinois | ||||||
| South Dakota State | at | Youngstown State | ||||||
| 10/11/2025 | South Dakota | at | Indiana State | |||||
| Illinois State | at | Murray State | ||||||
| Youngstown State | at | North Dakota | ||||||
| Southern Illinois | at | North Dakota State | ||||||
| Northern Iowa | at | South Dakota State | ||||||
| 10/18/2025 | Youngstown State | at | Illinois State | |||||
| North Dakota State | at | Indiana State | ||||||
| South Dakota State | at | Murray State | ||||||
| South Dakota | at | Northern Iowa | ||||||
| North Dakota | at | Southern Illinois | ||||||
| 10/25/2025 | Indiana State | at | North Dakota | |||||
| Illinois State | at | South Dakota | ||||||
| North Dakota State | at | South Dakota State | ||||||
| Northern Iowa | at | Southern Illinois | ||||||
| Murray State | at | Youngstown State | ||||||
| 11/1/2025 | Northern Iowa | at | Illinois State | |||||
| Southern Illinois | at | Murray State | ||||||
| Youngstown State | at | North Dakota State | ||||||
| North Dakota | at | South Dakota | ||||||
| Indiana State | at | South Dakota State | ||||||
| 11/8/2025 | Illinois State | at | Indiana State | |||||
| North Dakota State | at | North Dakota | ||||||
| Murray State | at | Northern Iowa | ||||||
| South Dakota State | at | South Dakota | ||||||
| Southern Illinois | at | Youngstown State | ||||||
| 11/15/2025 | North Dakota | at | Murray State | |||||
| Northern Iowa | at | North Dakota State | ||||||
| Illinois State | at | South Dakota State | ||||||
| South Dakota | at | Southern Illinois | ||||||
| Indiana State | at | Youngstown State | ||||||
| 11/22/2025 | Southern Illinois | at | Illinois State | |||||
| Murray State | at | Indiana State | ||||||
| South Dakota State | at | North Dakota | ||||||
| St Thomas | at | North Dakota State | Pio | |||||
| Youngstown State | at | Northern Iowa |