| 8/28/2025 | Upper Iowa | at | Drake | @ Pio (1AA) | ||||
| McKendree | at | Indiana State | @ MVC (1AA) | |||||
| Indianapolis | at | Marian IN | @ MSFA (NAIA) | |||||
| Concordia-St Paul | at | Quincy | NSIC | |||||
| 8/30/2025 | William Jewell | at | Fort Lewis | @ RMAC | ||||
| Lincoln CA | at | Lincoln MO | None (Unk?) | |||||
| Central Methodist | at | Missouri S&T | HAAC (NAIA) | |||||
| Truman State | at | Washburn | @ MAIAA | |||||
| 9/6/2025 | Truman State | at | Butler | @ Pio (1AA) | ||||
| Indianapolis | at | Findlay | @ GMAC | |||||
| Lincoln MO | at | Lane | @ SIAC | |||||
| Hillsdale | at | McKendree | GMAC | |||||
| Missouri S&T | at | Northeastern State | @ D2Ind | |||||
| Quincy | at | Roosevelt | @ GLIAC | |||||
| Missouri Southern | at | Southwest Baptist | MAIAA | |||||
| 9/13/2025 | Ashland | at | Indianapolis | GMAC | ||||
| Missouri S&T | at | Missouri Western | @ MAIAA | |||||
| Southwest Baptist | at | Roosevelt | @ GLIAC | |||||
| Davenport | at | Truman State | GLIAC | |||||
| South Dakota Tech | at | Upper Iowa | RMAC | |||||
| Kentucky Wesleyan | at | William Jewell | GMAC | |||||
| 9/20/2025 | McKendree | at | Indianapolis | |||||
| Quincy | at | Lincoln MO | ||||||
| Upper Iowa | at | Michigan Tech | @ GLIAC | |||||
| Truman State | at | Missouri S&T | ||||||
| Southwest Baptist | at | William Jewell | ||||||
| 9/27/2025 | William Jewell | at | McKendree | |||||
| Missouri S&T | at | Southwest Baptist | ||||||
| Indianapolis | at | Truman State | ||||||
| Lincoln MO | at | Upper Iowa | ||||||
| Quincy | at | Wayne State MI | @ GLIAC | |||||
| 10/4/2025 | William Jewell | at | Indianapolis | |||||
| Southwest Baptist | at | Lincoln MO | ||||||
| Upper Iowa | at | Missouri S&T | ||||||
| McKendree | at | Quincy | ||||||
| 10/11/2025 | Northeastern State | at | Lincoln MO | D2Ind | ||||
| Indianapolis | at | Missouri S&T | ||||||
| McKendree | at | Southwest Baptist | ||||||
| Upper Iowa | at | Truman State | ||||||
| Quincy | at | William Jewell | ||||||
| 10/18/2025 | Lincoln MO | at | Indianapolis | |||||
| Missouri S&T | at | McKendree | ||||||
| Quincy | at | Truman State | ||||||
| Southwest Baptist | at | Upper Iowa | ||||||
| Northeastern State | at | William Jewell | D2Ind | |||||
| 10/25/2025 | Lincoln MO | at | McKendree | |||||
| Missouri S&T | at | Quincy | ||||||
| Truman State | at | Southwest Baptist | ||||||
| Upper Iowa | at | William Jewell | ||||||
| 11/1/2025 | Truman State | at | Lincoln MO | |||||
| William Jewell | at | Missouri S&T | ||||||
| Indianapolis | at | Quincy | ||||||
| McKendree | at | Upper Iowa | ||||||
| 11/8/2025 | Missouri S&T | at | Lincoln MO | |||||
| McKendree | at | Northeastern State | @ D2Ind | |||||
| Indianapolis | at | Southwest Baptist | ||||||
| William Jewell | at | Truman State | ||||||
| Quincy | at | Upper Iowa | ||||||
| 11/15/2025 | Upper Iowa | at | Indianapolis | |||||
| Truman State | at | McKendree | ||||||
| Southwest Baptist | at | Quincy | ||||||
| Lincoln MO | at | William Jewell |