| 8/30/2025 | Gettysburg | at | Shenandoah | @ ODC | ||||
| 9/4/2025 | Franklin & Marshall | at | Lebanon Valley | @ MidAC | ||||
| 9/5/2025 | Ursinus | at | Alvernia | @ MidAC | ||||
| McDaniel | at | Catholic | @ LM | |||||
| Juniata | at | Gettysburg | LM | |||||
| Moravian | at | Muhlenberg | LM | |||||
| Dickinson | at | Randolph-Macon | @ ODC | |||||
| 9/6/2025 | Carnegie Mellon | at | Chicago | @ MidW | ||||
| Johns Hopkins | at | Ithaca | @ LL | |||||
| 9/13/2025 | Wisconsin-La Crosse | at | Carnegie Mellon | WIAC | ||||
| Waynesburg | at | Dickinson | TPAC | |||||
| Muhlenberg | at | Endicott | @ CNE | |||||
| Westminster PA | at | Franklin & Marshall | TPAC | |||||
| Christopher Newport | at | Gettysburg | NJAC | |||||
| John Carroll | at | Johns Hopkins | NCA | |||||
| Salisbury | at | McDaniel | NJAC | |||||
| Kean | at | Ursinus | NJAC | |||||
| 9/20/2025 | Berry | at | Carnegie Mellon | SAA | ||||
| Catholic | at | Franklin & Marshall | LM | |||||
| Dickinson | at | Lycoming | @ LM | |||||
| Juniata | at | McDaniel | LM | |||||
| Ursinus | at | Moravian | @ LM | |||||
| Johns Hopkins | at | Susquehanna | @ LM | |||||
| Gettysburg | at | Western Connecticut | @ LM | |||||
| Muhlenberg | at | Wilkes | @ LM | |||||
| 10/3/2025 | Dickinson | at | Johns Hopkins | |||||
| 10/4/2025 | McDaniel | at | Carnegie Mellon | |||||
| Franklin & Marshall | at | Gettysburg | ||||||
| Ursinus | at | Muhlenberg | ||||||
| 10/11/2025 | Gettysburg | at | Dickinson | |||||
| Muhlenberg | at | Franklin & Marshall | ||||||
| Carnegie Mellon | at | Johns Hopkins | ||||||
| McDaniel | at | Ursinus | ||||||
| 10/18/2025 | Gettysburg | at | Carnegie Mellon | |||||
| Franklin & Marshall | at | Dickinson | ||||||
| Ursinus | at | Johns Hopkins | ||||||
| Muhlenberg | at | McDaniel | ||||||
| 10/25/2025 | Johns Hopkins | at | Gettysburg | |||||
| Dickinson | at | McDaniel | ||||||
| Carnegie Mellon | at | Muhlenberg | ||||||
| Franklin & Marshall | at | Ursinus | ||||||
| 11/1/2025 | Carnegie Mellon | at | Dickinson | |||||
| McDaniel | at | Franklin & Marshall | ||||||
| Johns Hopkins | at | Muhlenberg | ||||||
| Gettysburg | at | Ursinus | ||||||
| 11/8/2025 | Franklin & Marshall | at | Carnegie Mellon | |||||
| Ursinus | at | Dickinson | ||||||
| Muhlenberg | at | Gettysburg | ||||||
| McDaniel | at | Johns Hopkins | ||||||
| 11/15/2025 | Johns Hopkins | at | Franklin & Marshall | |||||
| Gettysburg | at | McDaniel | ||||||
| Dickinson | at | Muhlenberg | ||||||
| Carnegie Mellon | at | Ursinus |