| 8/23/2025 | Kansas State | vs | Iowa State | Dublin IE | ||||
| Fresno State | at | Kansas | MW | |||||
| 8/28/2025 | Jacksonville State | at | UCF | CUSA | ||||
| Stephen F. Austin | at | Houston | SLC (1AA) | |||||
| Cincinnati | vs | Nebraska | Kansas City MO | vs B10 | ||||
| Tennessee-Martin | at | Oklahoma State | BigS (1AA) | |||||
| 8/29/2025 | Auburn | at | Baylor | SEC | ||||
| Georgia Tech | at | Colorado | ACC | |||||
| Wagner | at | Kansas | NE (1AA) | |||||
| 8/30/2025 | Hawaii | at | Arizona | MW | ||||
| Northern Arizona | at | Arizona State | BSky (1AA) | |||||
| Portland State | at | BYU | BSky (1AA) | |||||
| South Dakota | at | Iowa State | MVC (1AA) | |||||
| North Dakota | at | Kansas State | MVC (1AA) | |||||
| Ark Pine Bluff | at | Texas Tech | SWAC (1AA) | |||||
| Utah | at | UCLA | @ B10 | |||||
| Robert Morris | at | West Virginia | NE (1AA) | |||||
| 9/1/2025 | TCU | at | North Carolina | @ ACC | ||||
| 9/6/2025 | Weber State | at | Arizona | BSky (1AA) | ||||
| Stanford | at | BYU | ACC | |||||
| North Carolina A&T | at | UCF | CAAF (1AA) | |||||
| Bowling Green | at | Cincinnati | MAC | |||||
| Delaware | at | Colorado | CUSA | |||||
| Iowa | at | Iowa State | B10 | |||||
| Army | at | Kansas State | AAC | |||||
| Arizona State | at | Mississippi State | @ SEC | |||||
| Kansas | at | Missouri | @ SEC | |||||
| West Virginia | at | Ohio | @ MAC | |||||
| Oklahoma State | at | Oregon | @ B10 | |||||
| Houston | at | Rice | @ AAC | |||||
| Baylor | at | SMU | @ ACC | |||||
| Kent State | at | Texas Tech | MAC | |||||
| Cal Poly | at | Utah | BSky (1AA) | |||||
| 9/12/2025 | Kansas State | at | Arizona | |||||
| Colorado | at | Houston | ||||||
| 9/13/2025 | Texas State | at | Arizona State | SBC | ||||
| Iowa State | at | Arkansas State | @ SBC | |||||
| Samford | at | Baylor | SoCon (1AA) | |||||
| Northwestern State | at | Cincinnati | SLC (1AA) | |||||
| Abilene Christian | at | TCU | UAC (1AA) | |||||
| Oregon State | at | Texas Tech | Ind | |||||
| Pittsburgh | at | West Virginia | ACC | |||||
| Utah | at | Wyoming | @ MW | |||||
| 9/19/2025 | Tulsa | at | Oklahoma State | AAC | ||||
| 9/20/2025 | Arizona State | at | Baylor | |||||
| North Carolina | at | UCF | ACC | |||||
| Wyoming | at | Colorado | MW | |||||
| BYU | at | East Carolina | @ AAC | |||||
| West Virginia | at | Kansas | ||||||
| SMU | at | TCU | ACC | |||||
| Texas Tech | at | Utah | ||||||
| 9/26/2025 | TCU | at | Arizona State | |||||
| Houston | at | Oregon State | @ Ind | |||||
| 9/27/2025 | BYU | at | Colorado | |||||
| Arizona | at | Iowa State | ||||||
| Cincinnati | at | Kansas | ||||||
| UCF | at | Kansas State | ||||||
| Baylor | at | Oklahoma State | ||||||
| Utah | at | West Virginia | ||||||
| 10/3/2025 | West Virginia | at | BYU | |||||
| 10/4/2025 | Oklahoma State | at | Arizona | |||||
| Kansas State | at | Baylor | ||||||
| Kansas | at | UCF | ||||||
| Iowa State | at | Cincinnati | ||||||
| Texas Tech | at | Houston | ||||||
| Colorado | at | TCU | ||||||
| 10/11/2025 | BYU | at | Arizona | |||||
| UCF | at | Cincinnati | ||||||
| Iowa State | at | Colorado | ||||||
| TCU | at | Kansas State | ||||||
| Houston | at | Oklahoma State | ||||||
| Kansas | at | Texas Tech | ||||||
| Arizona State | at | Utah | ||||||
| 10/18/2025 | Texas Tech | at | Arizona State | |||||
| Utah | at | BYU | ||||||
| West Virginia | at | UCF | ||||||
| Arizona | at | Houston | ||||||
| Cincinnati | at | Oklahoma State | ||||||
| Baylor | at | TCU | ||||||
| 10/25/2025 | Houston | at | Arizona State | |||||
| Baylor | at | Cincinnati | ||||||
| BYU | at | Iowa State | ||||||
| Kansas State | at | Kansas | ||||||
| Oklahoma State | at | Texas Tech | ||||||
| Colorado | at | Utah | ||||||
| TCU | at | West Virginia | ||||||
| 11/1/2025 | UCF | at | Baylor | |||||
| Arizona | at | Colorado | ||||||
| West Virginia | at | Houston | ||||||
| Arizona State | at | Iowa State | ||||||
| Oklahoma State | at | Kansas | ||||||
| Texas Tech | at | Kansas State | ||||||
| Cincinnati | at | Utah | ||||||
| 11/7/2025 | Houston | at | UCF | |||||
| 11/8/2025 | Kansas | at | Arizona | |||||
| Iowa State | at | TCU | ||||||
| BYU | at | Texas Tech | ||||||
| Colorado | at | West Virginia | ||||||
| 11/15/2025 | West Virginia | at | Arizona State | |||||
| Utah | at | Baylor | ||||||
| TCU | at | BYU | ||||||
| Arizona | at | Cincinnati | ||||||
| Kansas State | at | Oklahoma State | ||||||
| UCF | at | Texas Tech | ||||||
| 11/22/2025 | Baylor | at | Arizona | |||||
| Oklahoma State | at | UCF | ||||||
| BYU | at | Cincinnati | ||||||
| Arizona State | at | Colorado | ||||||
| TCU | at | Houston | ||||||
| Kansas | at | Iowa State | ||||||
| Kansas State | at | Utah | ||||||
| 11/28/2025 | Arizona | at | Arizona State | |||||
| Utah | at | Kansas | ||||||
| 11/29/2025 | Houston | at | Baylor | |||||
| UCF | at | BYU | ||||||
| Colorado | at | Kansas State | ||||||
| Iowa State | at | Oklahoma State | ||||||
| Cincinnati | at | TCU | ||||||
| Texas Tech | at | West Virginia |