| 9/7/2024 | Guilford | 14 | at | Greensboro (1-7) | 0 | at USASC | ||
| 9/14/2024 | Methodist (1-8) | 12 | at | Guilford | 14 | USASC | ||
| 9/21/2024 | Sewanee (2-6) | 35 | at | Guilford | 44 | SAA | ||
| 10/5/2024 | Guilford | 0 | at | Hampden-Sydney (5-3,3-2) | 31 | |||
| 10/12/2024 | Guilford | 0 | at | Randolph-Macon (7-1,5-0) | 63 | |||
| 10/19/2024 | Washington and Lee (4-3,4-1) | 40 | at | Guilford | 23 | |||
| 10/26/2024 | Guilford | 10 | at | Shenandoah (6-2,3-2) | 42 | |||
| 11/2/2024 | Ferrum (4-4,3-3) | 20 | at | Guilford | 7 | |||
| 11/9/2024 | Guilford | at | Averett (2-6,0-6) | |||||
| 11/16/2024 | Bridgewater VA (5-3,3-2) | at | Guilford |
| vs Guilford | vs Other Opponents | Guilford compared to OOs | |
| Record: | 5-3 | 32-40 | |
| Points Scored: | 30.38 | 25.32 | -5.06 |
| Points Allowed: | 14.00 | 27.46 | -13.46 |
| Margin: | 16.38 | -2.14 | -18.52 |
| Total Points: | 44.38 | 52.78 | -8.40 |