| 9/2/2023 | King's (8-3) | 27 | at | Wilkes | 23 | MidAC | ||
| 9/9/2023 | Wilkes | 14 | at | Rensselaer (8-3) | 38 | at LL | ||
| 9/16/2023 | Brockport State (8-3) | 31 | at | Wilkes | 7 | E8 | ||
| 9/23/2023 | Wilkes | 20 | at | St John Fisher (5-5) | 29 | at E8 | ||
| 9/30/2023 | Juniata (1-9,0-6) | 14 | at | Wilkes | 63 | |||
| 10/7/2023 | Wilkes | 48 | at | Lycoming (5-6,4-2) | 35 | |||
| 10/14/2023 | Keystone (2-8,1-5) | 7 | at | Wilkes | 42 | |||
| 10/21/2023 | Wilkes | 7 | at | Susquehanna (10-1,6-0) | 34 | |||
| 11/4/2023 | Catholic (5-5,3-3) | 40 | at | Wilkes | 35 | |||
| 11/11/2023 | Wilkes | 41 | at | Moravian (4-6,3-3) | 6 | |||
| 11/18/2023 | Bridgewater VA (7-4) | 17 | at | Wilkes | 35 | Cape Henry Bowl | ODC |
| vs Wilkes | vs Other Opponents | Wilkes compared to OOs | |
| Record: | 6-5 | 57-48 | |
| Points Scored: | 25.27 | 28.06 | 2.79 |
| Points Allowed: | 30.45 | 24.79 | 5.66 |
| Margin: | -5.18 | 3.27 | 8.45 |
| Total Points: | 55.72 | 52.85 | 2.87 |