| 9/2/2023 | Prairie View | 37 | at | Texas Southern (3-8,2-6) | 34 | OT | ||
| 9/9/2023 | Abilene Christian (5-6) | 45 | at | Prairie View | 16 | ASUN | ||
| 9/16/2023 | Prairie View | 0 | at | SMU (11-3) | 69 | at AAC | ||
| 9/23/2023 | Prairie View | 23 | at | Alcorn State (7-4,6-2) | 20 | |||
| 9/30/2023 | Prairie View | 20 | vs | Grambling (5-6,4-4) | 35 | Dallas TX | ||
| 10/7/2023 | Mississippi Valley State (1-10,1-7) | 12 | at | Prairie View | 31 | |||
| 10/14/2023 | Prairie View | 0 | at | Houston Christian (5-5) | 30 | at SLC | ||
| 10/28/2023 | Prairie View | 7 | at | Florida A&M (12-1,9-0) | 45 | |||
| 11/4/2023 | Ark Pine Bluff (2-9,1-7) | 14 | at | Prairie View | 38 | |||
| 11/11/2023 | Prairie View | 27 | at | Southern (6-5,5-5) | 21 | |||
| 11/18/2023 | Alabama State (7-4,6-3) | 14 | at | Prairie View | 21 | |||
| 12/2/2023 | Prairie View | 14 | at | Florida A&M (12-1,9-0) | 35 | SWAC Championship |
| vs Prairie View | vs Other Opponents | Prairie View compared to OOs | |
| Record: | 6-6 | 68-56 | |
| Points Scored: | 31.17 | 25.34 | -5.83 |
| Points Allowed: | 19.50 | 24.02 | -4.52 |
| Margin: | 11.67 | 1.32 | -10.35 |
| Total Points: | 50.67 | 49.36 | 1.31 |