| 8/28/2021 | Sterling | 38 | at | Midland U. (6-5) | 36 | at GPAC | ||
| 9/4/2021 | St Mary KS (3-7,3-7) | 10 | at | Sterling | 49 | |||
| 9/11/2021 | Sterling | 7 | at | Kansas Wesleyan (10-2,9-1) | 31 | |||
| 9/25/2021 | Sterling | 45 | at | Tabor (3-8,2-8) | 18 | |||
| 10/2/2021 | Avila (7-3,7-3) | 34 | at | Sterling | 31 | |||
| 10/9/2021 | Sterling | 50 | at | Bethany KS (0-10,0-10) | 7 | |||
| 10/16/2021 | Friends (1-9,1-9) | 14 | at | Sterling | 42 | |||
| 10/23/2021 | Bethel KS (9-2,9-1) | 42 | at | Sterling | 21 | |||
| 10/30/2021 | Sterling | 14 | at | Southwestern (9-2,9-1) | 42 | |||
| 11/6/2021 | Ottawa (5-6,4-6) | 6 | at | Sterling | 21 | |||
| 11/13/2021 | Sterling | 28 | at | McPherson (6-4,6-4) | 48 | |||
| 11/20/2021 | Sterling | 14 | at | Southwestern Assemblies of God (9-3) | 31 | at Soon |
| vs Sterling | vs Other Opponents | Sterling compared to OOs | |
| Record: | 6-6 | 62-55 | |
| Points Scored: | 26.58 | 30.11 | 3.53 |
| Points Allowed: | 30.00 | 27.69 | 2.31 |
| Margin: | -3.42 | 2.42 | 5.84 |
| Total Points: | 56.58 | 57.80 | -1.22 |