| 9/3/2021 | Alvernia | 6 | at | Ursinus (7-4) | 42 | at Cen | ||
| 9/11/2021 | Alvernia | 14 | at | Hartwick (2-7) | 23 | at E8 | ||
| 9/18/2021 | Albright (2-8,1-7) | 31 | at | Alvernia | 21 | |||
| 9/25/2021 | Alvernia | 0 | at | Wilkes (6-4,5-4) | 23 | |||
| 10/2/2021 | Alvernia | 7 | at | King's (5-5,4-5) | 10 | |||
| 10/9/2021 | Widener (7-4,5-3) | 37 | at | Alvernia | 7 | |||
| 10/16/2021 | Alvernia | 10 | at | Lebanon Valley (5-5,4-5) | 31 | |||
| 10/30/2021 | Stevenson (5-6,5-3) | 35 | at | Alvernia | 6 | |||
| 11/6/2021 | Alvernia | 14 | at | Fairleigh Dickinson-Florham (7-4,5-3) | 34 | |||
| 11/13/2021 | Lycoming (8-3,7-2) | 48 | at | Alvernia | 0 |
| vs Alvernia | vs Other Opponents | Alvernia compared to OOs | |
| Record: | 10-0 | 44-50 | |
| Points Scored: | 31.40 | 22.45 | -8.95 |
| Points Allowed: | 8.50 | 25.19 | -16.69 |
| Margin: | 22.90 | -2.74 | -25.64 |
| Total Points: | 39.90 | 47.64 | -7.74 |