| 9/2/2021 | Bemidji State | 24 | at | Sioux Falls (8-3,8-3) | 16 | | | |
| 9/11/2021 | Wayne State NE (7-4,7-4) | 28 | at | Bemidji State | 38 | | | |
| 9/18/2021 | Bemidji State | 24 | at | Minnesota State-Mankato (6-5,6-5) | 45 | | | |
| 9/25/2021 | Augustana SD (9-3,9-3) | 52 | at | Bemidji State | 24 | | | |
| 10/2/2021 | Minot State (2-9,2-9) | 35 | at | Bemidji State | 49 | | | |
| 10/9/2021 | Bemidji State | 42 | at | Concordia-St Paul (1-10,1-10) | 14 | | | |
| 10/16/2021 | Minnesota State-Moorhead (5-6,5-6) | 19 | at | Bemidji State | 22 | | | |
| 10/23/2021 | Bemidji State | 42 | at | Minnesota-Duluth (9-3,9-2) | 35 | | | |
| 10/30/2021 | Southwest Minnesota State (2-9,2-9) | 14 | at | Bemidji State | 48 | | | |
| 11/6/2021 | Bemidji State | 36 | at | Northern State (7-4,7-4) | 34 | | | |
| 11/13/2021 | Mary (4-7,4-7) | 40 | at | Bemidji State | 62 | | | |
| 11/20/2021 | Bemidji State | 28 | at | Augustana SD (9-3,9-3) | 24 | | | |
| 11/27/2021 | Bemidji State | 6 | at | Colorado Mines (12-2) | 55 | | | at RMAC |