| 9/4/2021 | Montana (10-3) | 13 | at | Washington | 7 | BSky (1AA) | ||
| 9/11/2021 | Washington | 10 | at | Michigan (12-2) | 31 | at B10 | ||
| 9/18/2021 | Arkansas State (2-10) | 3 | at | Washington | 52 | SBC | ||
| 9/25/2021 | California (5-7,4-5) | 24 | at | Washington | 31 | OT | ||
| 10/2/2021 | Washington | 24 | at | Oregon State (7-6,5-4) | 27 | |||
| 10/16/2021 | UCLA (8-4,6-3) | 24 | at | Washington | 17 | |||
| 10/22/2021 | Washington | 21 | at | Arizona (1-11,1-8) | 16 | |||
| 10/30/2021 | Washington | 20 | at | Stanford (3-9,2-7) | 13 | |||
| 11/6/2021 | Oregon (10-4,7-3) | 26 | at | Washington | 16 | |||
| 11/13/2021 | Arizona State (8-5,6-3) | 35 | at | Washington | 30 | |||
| 11/20/2021 | Washington | 17 | at | Colorado (4-8,3-6) | 20 | |||
| 11/26/2021 | Washington State (7-6,6-3) | 40 | at | Washington | 13 |
| vs Washington | vs Other Opponents | Washington compared to OOs | |
| Record: | 8-4 | 69-71 | |
| Points Scored: | 22.67 | 27.81 | 5.14 |
| Points Allowed: | 21.50 | 25.95 | -4.45 |
| Margin: | 1.17 | 1.86 | 0.69 |
| Total Points: | 44.17 | 53.76 | -9.59 |