| 9/5/2015 | Glenville State (7-4,6-4) | 49 | at | Urbana | 0 | | | |
| 9/12/2015 | Urbana | 30 | at | West Virginia State (5-6,5-5) | 23 | | | |
| 9/19/2015 | Concord (5-5,5-5) | 23 | at | Urbana | 7 | | | |
| 9/24/2015 | Urbana | 12 | at | West Liberty (5-6,5-5) | 28 | | | |
| 10/3/2015 | Fairmont State (6-4,6-4) | 6 | at | Urbana | 0 | | | |
| 10/10/2015 | Urbana | 33 | at | Lake Erie (3-8) | 30 | | | at GLIAC |
| 10/17/2015 | Urbana | 7 | at | West Virginia Wesleyan (2-8,2-8) | 34 | | | |
| 10/24/2015 | Charleston WV (10-2,9-1) | 37 | at | Urbana | 12 | | | |
| 10/31/2015 | Urbana | 19 | at | Virginia-Wise (1-10,1-9) | 24 | | | |
| 11/7/2015 | Notre Dame OH (5-6,5-5) | 47 | at | Urbana | 30 | | | |
| 11/14/2015 | Urbana | 20 | at | Shepherd (13-1,10-0) | 52 | | | |