| 9/3/2015 | Northwestern Oklahoma State | 52 | at | Arkansas-Monticello (1-10,1-10) | 31 | | | |
| 9/12/2015 | Southern Arkansas (7-4,7-4) | 49 | at | Northwestern Oklahoma State | 14 | | | |
| 9/19/2015 | Henderson State (11-2,10-1) | 25 | at | Northwestern Oklahoma State | 17 | | | |
| 9/26/2015 | Northwestern Oklahoma State | 13 | at | Ouachita (7-4,7-4) | 55 | | | |
| 10/3/2015 | Northwestern Oklahoma State | 30 | at | East Central (6-5,6-5) | 42 | | | |
| 10/10/2015 | Southeastern Oklahoma State (6-5,6-5) | 16 | at | Northwestern Oklahoma State | 31 | | | |
| 10/17/2015 | Oklahoma Baptist (2-9,2-9) | 41 | at | Northwestern Oklahoma State | 38 | | | |
| 10/24/2015 | Northwestern Oklahoma State | 49 | at | Southern Nazarene (1-10,1-10) | 20 | | | |
| 10/31/2015 | Arkansas Tech (9-3,8-3) | 53 | at | Northwestern Oklahoma State | 21 | | | |
| 11/7/2015 | Northwestern Oklahoma State | 30 | at | Harding (7-4,7-4) | 42 | | | |
| 11/14/2015 | Southwestern Oklahoma State (8-4,8-3) | 31 | at | Northwestern Oklahoma State | 17 | | | |