| 9/5/2015 | Waynesburg (3-7) | 35 | at | Muskingum | 10 | TPAC | ||
| 9/19/2015 | Muskingum | 0 | at | Mount Union (15-0,9-0) | 56 | |||
| 9/26/2015 | Muskingum | 31 | at | Capital (3-7,3-6) | 34 | |||
| 10/3/2015 | Baldwin-Wallace (7-3,7-2) | 34 | at | Muskingum | 28 | |||
| 10/10/2015 | Heidelberg (5-5,5-4) | 52 | at | Muskingum | 7 | |||
| 10/17/2015 | Muskingum | 21 | at | Otterbein (4-6,4-5) | 28 | |||
| 10/24/2015 | Ohio Northern (9-3,7-2) | 42 | at | Muskingum | 7 | |||
| 10/31/2015 | Muskingum | 0 | at | John Carroll (8-2,7-2) | 30 | |||
| 11/7/2015 | Muskingum | 28 | at | Marietta (2-8,2-7) | 49 | |||
| 11/14/2015 | Wilmington (1-9,0-9) | 35 | at | Muskingum | 49 |
| vs Muskingum | vs Other Opponents | Muskingum compared to OOs | |
| Record: | 9-1 | 48-49 | |
| Points Scored: | 39.50 | 29.28 | -10.22 |
| Points Allowed: | 18.10 | 29.21 | -11.11 |
| Margin: | 21.40 | 0.07 | -21.33 |
| Total Points: | 57.60 | 58.49 | -0.89 |