| 8/31/2013 | Texas State (6-6) | 22 | at | Southern Miss | 15 | SBC | ||
| 9/7/2013 | Southern Miss | 13 | at | Nebraska (9-4) | 56 | at B10 | ||
| 9/14/2013 | Southern Miss | 3 | at | Arkansas (3-9) | 24 | at SEC | ||
| 9/28/2013 | Southern Miss | 7 | at | Boise State (8-5) | 60 | at MW | ||
| 10/5/2013 | Florida Intl (1-11,1-7) | 24 | at | Southern Miss | 23 | |||
| 10/19/2013 | Southern Miss | 14 | at | East Carolina (10-3,6-2) | 55 | |||
| 10/26/2013 | North Texas (9-4,6-2) | 55 | at | Southern Miss | 14 | |||
| 11/2/2013 | Southern Miss | 13 | at | Marshall (10-4,7-2) | 61 | |||
| 11/9/2013 | Southern Miss | 13 | at | Louisiana Tech (4-8,3-5) | 36 | |||
| 11/16/2013 | Florida Atlantic (6-6,4-4) | 41 | at | Southern Miss | 7 | |||
| 11/23/2013 | Middle Tenn State (8-5,6-2) | 42 | at | Southern Miss | 21 | |||
| 11/30/2013 | Southern Miss | 62 | at | UAB (2-10,1-7) | 27 |
| vs Southern Miss | vs Other Opponents | Southern Miss compared to OOs | |
| Record: | 11-1 | 65-74 | |
| Points Scored: | 41.92 | 27.39 | -14.53 |
| Points Allowed: | 17.08 | 28.09 | -11.01 |
| Margin: | 24.84 | -0.70 | -25.54 |
| Total Points: | 59.00 | 55.48 | 3.52 |