| 8/30/2012 | Seton Hill | 6 | at | Slippery Rock (6-5) | 52 | at PSAC | ||
| 9/8/2012 | Seton Hill | 31 | at | Urbana (7-4) | 34 | at GLV | ||
| 9/15/2012 | Shepherd (8-3,7-1) | 42 | at | Seton Hill | 6 | |||
| 9/22/2012 | Seton Hill | 17 | at | West Virginia Wesleyan (3-8,2-6) | 41 | |||
| 9/29/2012 | West Virginia State (2-9,1-7) | 21 | at | Seton Hill | 13 | |||
| 10/6/2012 | Seton Hill | 13 | at | Charleston WV (9-2,6-2) | 30 | |||
| 10/13/2012 | Concord (7-4,6-2) | 29 | at | Seton Hill | 26 | |||
| 10/20/2012 | Seton Hill | 47 | at | Fairmont State (4-6,4-4) | 54 | |||
| 10/27/2012 | West Liberty (6-5,4-4) | 41 | at | Seton Hill | 29 | |||
| 11/3/2012 | Saint Anselm (2-9) | 52 | at | Seton Hill | 45 | NE10 | ||
| 11/10/2012 | Seton Hill | 2 | at | Glenville State (6-5,6-2) | 58 |
| vs Seton Hill | vs Other Opponents | Seton Hill compared to OOs | |
| Record: | 11-0 | 49-60 | |
| Points Scored: | 41.27 | 24.95 | -16.32 |
| Points Allowed: | 21.36 | 26.94 | -5.58 |
| Margin: | 19.91 | -1.99 | -21.90 |
| Total Points: | 62.63 | 51.89 | 10.74 |