| 9/1/2012 | Tuskegee | 6 | vs | Alabama A&M (7-4) | 7 | Birmingham AL | vs SWAC | |
| 9/8/2012 | Johnson C Smith (6-4) | 17 | vs | Tuskegee | 35 | Atlanta GA | CIAA | |
| 9/15/2012 | Lane (5-5,3-5) | 17 | at | Tuskegee | 45 | |||
| 9/29/2012 | Fort Valley State (8-4,6-2) | 18 | at | Tuskegee | 48 | |||
| 10/6/2012 | Tuskegee | 21 | vs | Morehouse (3-7,2-5) | 14 | Columbus GA | ||
| 10/11/2012 | Tuskegee | 16 | at | Stillman (6-5,4-3) | 0 | |||
| 10/20/2012 | Kentucky State (2-8,0-7) | 0 | at | Tuskegee | 37 | |||
| 10/27/2012 | Tuskegee | 14 | at | Clark Atlanta (2-8,2-6) | 0 | |||
| 11/3/2012 | Tuskegee | 27 | at | Miles (7-4,5-2) | 17 | |||
| 11/10/2012 | Tuskegee | 55 | vs | Fort Valley State (8-4,6-2) | 24 | Atlanta GA | ||
| 11/22/2012 | Tuskegee | 27 | at | Alabama State (7-4) | 25 | at SWAC | ||
| 12/1/2012 | Elizabeth City State (8-4) | 28 | at | Tuskegee | 13 | CIAA |
| vs Tuskegee | vs Other Opponents | Tuskegee compared to OOs | |
| Record: | 2-10 | 67-49 | |
| Points Scored: | 13.92 | 26.11 | 12.19 |
| Points Allowed: | 28.67 | 24.76 | 3.91 |
| Margin: | -14.75 | 1.35 | 16.10 |
| Total Points: | 42.59 | 50.87 | -8.28 |