| 9/3/2011 | DePauw Tigers 23 @ Rose-Hulman 13 | |
| 9/17/2011 | Rose-Hulman 22 @ Kalamazoo Hornets 43 | |
| 9/24/2011 | Hanover Panthers 20 @ Rose-Hulman 31 | † |
| 10/1/2011 | Rose-Hulman 26 @ Manchester Spartans 20 | † |
| 10/8/2011 | Franklin Grizzlies 55 @ Rose-Hulman 24 | † |
| 10/15/2011 | Mt St Joseph Lions 14 @ Rose-Hulman 20 | † |
| 10/22/2011 | Rose-Hulman 13 @ Bluffton Beavers 31 | † |
| 10/29/2011 | Defiance Yellow Jackets 21 @ Rose-Hulman 18 | † |
| 11/5/2011 | Rose-Hulman 53 @ Anderson Ravens 50 | † |
| 11/12/2011 | Rose-Hulman 21 @ Earlham Hustlin' Quakers 7 | † |