| 9/3/2011 | Centre 38 @ Hanover Panthers 21 | |
| 9/17/2011 | Washington and Lee Generals 35 @ Centre 42 | |
| 9/24/2011 | Austin Kangaroos 0 @ Centre 45 | † |
| 10/1/2011 | Centre 24 @ DePauw Tigers 10 | |
| 10/15/2011 | Centre 45 @ Birmingham-Southern Panthers 20 | † |
| 10/22/2011 | Sewanee Tigers 14 @ Centre 28 | † |
| 10/29/2011 | Centre 24 @ Millsaps Majors 22 | † |
| 11/5/2011 | Centre 14 @ Trinity TX Tigers 20 | † |
| 11/12/2011 | Rhodes Lynx 28 @ Centre 41 | † |
| 11/19/2011 | Hampden-Sydney Tigers 41 @ Centre 51 ( D3 playoff round 1 ) | |
| 11/26/2011 | Centre 10 @ Mount Union Purple Raiders 30 ( D3 playoff round 2 ) |