| 9/3/2011 | South Florida | 23 | at | #24 Notre Dame | 20 | ||
| 9/10/2011 | #24 Notre Dame | 31 | at | #11 Michigan | 35 | ||
| 9/17/2011 | #18 Michigan State | 13 | at | #24 Notre Dame | 31 | ||
| 9/24/2011 | #24 Notre Dame | 15 | at | Pittsburgh | 12 | ||
| 10/1/2011 | #24 Notre Dame | 38 | at | Purdue | 10 | ||
| 10/8/2011 | Air Force | 33 | at | #24 Notre Dame | 59 | ||
| 10/22/2011 | #10 Southern California | 31 | at | #24 Notre Dame | 17 | ||
| 10/29/2011 | Navy | 14 | at | #24 Notre Dame | 56 | ||
| 11/5/2011 | #24 Notre Dame | 24 | at | Wake Forest | 17 | ||
| 11/12/2011 | Maryland | 21 | vs | #24 Notre Dame | 45 | Landover MD | |
| 11/19/2011 | Boston College | 14 | at | #24 Notre Dame | 16 | ||
| 11/26/2011 | #24 Notre Dame | 14 | at | #5 Stanford | 28 | ||
| 12/29/2011 | Florida State | 18 | vs | #24 Notre Dame | 14 | Champs Sports Bowl |